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GLP: Good Laboratory Practice

GLP: Good Laboratory Practice
1. Introduction
In the early 70’s FDA (United States Food and Drug administration) have realized cases of poor laboratory practice throughout the United States. FDA decided to check over 40 toxicology labs in-depth. They revealed lot dishonest activities and a lot of poor lab practices. Examples of some of these poor lab practices found were equipment not been calibrated to standard form, therefore giving wrong measurements, incorrect or inaccurate accounts of the actual lab study and incompetent test systems. Although the term “good laboratory practice” might have been used informal already for some time in many laboratories around the world GLP originated in the United States and it had a powerfull effect world wide.
2. History of Good Laboratory Practice (GLP)

GLP is an official regulation that was created by the FDA in 1978. The OECD (Organisation for Economic Co-operation and Development) Principles of Good Laboratory Practice were first created by an Expert Group on GLP set up in 1978 under the Special Programme on the Control of Chemicals. The GLP regulations that are accepted as international standards for non-clinical laboratory studies published by the US Food and Drug Administration in 1976 supplied the basis for the work of the Expert Group, which was guided by the United States and consisted experts from the following countries and organisations:

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